AnimaPulse

Rabbit vaccination

Many owners do not know a rabbit can be vaccinated at all. Two diseases, almost always fatal, and a yearly booster that keeps both away.

These schedules are indicative, and this is a field that has moved recently with new RHD variants: your vet always has the final say.

United Kingdom

VaccinePrimary courseFirst boosterThen
Myxomatosis-RHDone yearly jab covering myxomatosis, RHD1 and RHD25 weeks1 year after the primary courseevery year

Ireland

VaccinePrimary courseFirst boosterThen
Myxomatosis-RHDmyxomatosis and rabbit haemorrhagic disease (RHDV1 and RHDV2) — both circulate in Ireland, yearly booster5 weeks1 year after the primary courseevery year

United States

VaccinePrimary courseFirst boosterThen
RHDV2deadly rabbit hemorrhagic disease — two doses three weeks apart, then a yearly booster7 weeks, 10 weeks1 year after the primary courseevery year

Australia

VaccinePrimary courseFirst boosterThen
Calicivirusrabbit haemorrhagic disease (calicivirus), fatal — yearly booster. No myxomatosis vaccine exists in Australia10 weeks1 year after the primary courseevery year

Two diseases, and why they frighten

Myxomatosis is spread by biting insects — mosquitoes, fleas — and by direct contact. It causes the characteristic swelling of the head and eyelids, and is very often fatal in pet rabbits.

RHD (rabbit haemorrhagic disease) is more brutal still: it frequently kills within 48 hours, sometimes with no warning signs at all. The virus is extremely hardy in the environment and spreads indirectly — on hay, on greens picked outdoors, on shoes, on hands.

That last point is what surprises people most: a rabbit that never goes outside can still catch RHD. The virus does not need the rabbit to go out; something only has to come in.

Where the countries differ

In Britain, combined vaccines covering myxomatosis and RHD (including the RHDV2 variant) are established, usually with a yearly booster. In the United States, the RHDV2 vaccine arrived more recently and under a conditional licence — availability and practice vary by state, and myxomatosis is not a routine concern in the same way.

Australia is the exception that surprises everyone: there is no myxomatosis vaccine there at all. It is not a supply problem. The myxoma virus is used in Australia to control wild rabbit populations, and a vaccine that protected pet rabbits would undermine that programme — so none is registered. Australian rabbits are vaccinated against calicivirus (RHD) only, and owners are advised to protect against myxomatosis by other means: insect screens, mosquito control, keeping rabbits in at dawn and dusk.

In Ireland, both diseases circulate: the Department of Agriculture lists myxomatosis and RHD as present, RHDV2 having been diagnosed there since 2016. The combined vaccine is given yearly, as in Britain — and note that Filavac, the French reference product, holds no Irish licence.

Canada is absent from this page on purpose. The RHDV2 vaccine only enters the country under emergency import authorisation, so there is no routine schedule to publish — and AnimaPulse would rather say nothing than invent one.

If you move a rabbit between countries, this is a conversation to have with a vet in advance.

A rabbit is not a small cat

That is the difficulty with pet rabbits: they need a specific kind of medicine that not every practice offers. A vet used to exotic pets will spot signs a generalist may miss — and rabbits, as prey animals, hide pain until the last moment. A rabbit that stops eating is an emergency, not a mood.

Other exotic pets

Ferrets have an established protocol — see the dedicated page. For most other small pets (guinea pigs, rodents, birds, reptiles) there is no routine vaccination. That does not make veterinary follow-up pointless: the annual check-up remains the best preventive tool there is, and AnimaPulse lets you schedule it like anything else.

Sources — United Kingdom

Sources — United States

Sources — Australia

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Page updated on 8 August 2026.